This study aimed to report a beneficial use of polyphenols from Egyptian corn silk waste and their encapsulation in polymeric nanoparticles (NPs) as nanocargo with enhanced antioxidant and antibacterial properties. Different formulations of encapsulated NPs with an increasing silk extract (SE) concentrations (SE x\CS NPs), where x= 0.5, 1, 1.5, and 2 mg/mL, were prepared. DLS and SEM data showed their z-diameter values up to 77 nm. FTIR spectroscopy analysis confirmed the successful encapsulation of the corn silk extract in CS NPs. The cumulative SE release % was compared in pH 7.4 and 5.8 showing a faster release profile of the earlier pH. The highest free radical scavenging activity of the nanocagro formulations was 95.4%. While, their highest total phenolic contents (TPC) values was 3.7 mg GAE/g sample. Finally, their antibacterial activity against Escherichia coli (E.coli) showed 98.27% bacterial growth inhibition (BGI) while demonstrating a complete BGI against Staphylococcus aureus (S. aureus).

Corn silk polyphenols encapsulated in polymeric nano-formulation: Food waste recycling to produce a promising antioxidant and antibacterial biomaterials

ACS Fall 2021

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