Energy transfer photocatalysis has gained interest in recent years for mild access to triplet excited state substrates which can undergo a variety of useful reactions such as cycloadditions. The use of this strategy in the synthesis of heterocycles has focused on four-membered systems such as azetidines and oxetanes through [2+2] cycloadditions. While access to these products is important, this strategy offers benefits which would be desirable in the synthesis of other biologically relevant or synthetically useful heterocycles. However, utilization of the resulting [2+2] cycloaddition products as an intermediate to access different desirable heterocycles has not yet been thoroughly explored. This work reports the use of visible light energy transfer photocatalysis to leverage the reactivity of initial [2+2] cycloaddition products to access other heterocycles in a mild and atom efficient manner.

Exploration of energy transfer photocatalysis in the synthesis of desirable small heterocycles

ACS Fall 2021

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.