This research focused on the use of disproportionality analysis between different NSAIDs and 3 cancer types using FAERS data.
The MedDRA terms considered for benefit were “breast cancer”, “colorectal cancer”, “malignant melanoma”, for risk: “gastrointestinal disorders”, “cardiovascular disorders" and "renal disorders". Proportional reporting ratios (PRR) for B-R were calculated for each NSAID and cancer.
Results suggest specific benefit-risk for certain NSAIDs and triggers the need for additional RWE research in this field.

The use of disproportionality to document the benefit-risk profile of NSAIDs in breast, colorectal and skin (melanoma) cancer

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Join the DIA Pharmacovigilance Strategies Workshop to discuss the current landscape and join intense and well-lead discussion that may help you to progress your knowledge and practices.

The conference format is designed to stimulate dialogue and generate solutions through a series of interactive sessions and workshops conducted in an informal setting allowing for in-depth discussion in smaller groups.

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Pharmacovigilance Strategies Workshop

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