The chronic consumption of sweeteners has been associated with various metabolic disorders. In this study, the effect of chronic consumption (480 days) of nutritive and non-nutritive sweeteners on the levels of specific activity of acetyl coenzyme A carboxylase and fatty acid synthase in liver extracts of male and female rats of the Wistar strain was evaluated. Chronic consumption of drinks sweetened with glucose, sucrose, fructose and saccharin significantly increased (p <0.05) the activity levels of the enzymes acetyl coenzyme A carboxylase (ACC) and fatty acid synthase (FAS), suggesting an increase in the lipogenesis.

Efecto del consumo crónico de edulcorantes sobre los niveles de actividad de la acetil coenzima A carboxilasa y la sintasa de ácidos grasos en extractos hepáticos

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LatinXChem 2021

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.