Background
Oral desensitization is an emerging therapeutic option for food allergy. Safety and efficacy data of desensitization protocols are limited for baked egg (BE) and baked milk (BM).
Methods
A 5-year retrospective chart review of pediatric patients undergoing oral desensitization to BE and/or BM was conducted at a food allergy referral center.
Results
65 children underwent BE and/or BM oral desensitization from 2016-21. Oral desensitization involved initial low dose challenge (8-500mg BE protein; 15-166mg BM protein) with incremental dose escalation for baked muffin over an average 3.9 months. Median age at start of therapy was 6 years. Atopic history was notable for atopic dermatitis (92%), asthma (60%), allergic rhinitis (78%), prior anaphylaxis to food (49%), and prior anaphylaxis to egg or milk (36%). Mean baseline skin prick test (SPT) and food-specific IgE levels (sIgE) were: egg white SPT wheal diameter 9.6mm (3-17mm), egg white sIgE 17.0kU/L (1.0-70.9kU/L), ovomucoid sIgE 10.9kU/L (0.1-61.7kU/L), cow’s milk SPT 9.9mm (6-14mm), cow’s milk sIgE 24.3kU/L (2.0-67.5kU/L), and casein sIgE 22.8kU/L (0.5-78.4kU/L). Most participants reached maintenance, including 67% for BE (n=32, 1-2g BE protein) and 63% for BM (n=12, 660-1330mg BM protein). Reasons for discontinuing BE (n=8) included allergic symptoms (38%), allergy resolution (13%), scheduling (13%), anxiety (13%), boredom with muffin (13%), and unknown (13%). Reasons for discontinuing BM (n=3) included allergic symptoms (n=2) and unknown (n=1).
Conclusions
Most children undergoing BE and/or BM oral desensitization achieved maintenance. Reasons for discontinuation included dose-related allergic symptoms, especially with BM. Future studies optimizing protocols for BM and BE oral desensitization are encouraged.

**Background**
Oral desensitization is an emerging therapeutic option for food allergy. Safety and efficacy data of desensitization protocols are limited for baked egg (BE) and baked milk (BM).
**Methods**
A 5-year retrospective chart review of pediatric patients undergoing oral desensitization to BE and/or BM was conducted at a food allergy referral center.
**Results**
65 children underwent BE and/or BM oral desensitization from 2016-21. Oral desensitization involved initial low dose challenge (8-500mg BE protein; 15-166mg BM protein) with incremental dose escalation for baked muffin over an average 3.9 months. Median age at start of therapy was 6 years. Atopic history was notable for atopic dermatitis (92%), asthma (60%), allergic rhinitis (78%), prior anaphylaxis to food (49%), and prior anaphylaxis to egg or milk (36%). Mean baseline skin prick test (SPT) and food-specific IgE levels (sIgE) were: egg white SPT wheal diameter 9.6mm (3-17mm), egg white sIgE 17.0kU/L (1.0-70.9kU/L), ovomucoid sIgE 10.9kU/L (0.1-61.7kU/L), cow’s milk SPT 9.9mm (6-14mm), cow’s milk sIgE 24.3kU/L (2.0-67.5kU/L), and casein sIgE 22.8kU/L (0.5-78.4kU/L). Most participants reached maintenance, including 67% for BE (n=32, 1-2g BE protein) and 63% for BM (n=12, 660-1330mg BM protein). Reasons for discontinuing BE (n=8) included allergic symptoms (38%), allergy resolution (13%), scheduling (13%), anxiety (13%), boredom with muffin (13%), and unknown (13%). Reasons for discontinuing BM (n=3) included allergic symptoms (n=2) and unknown (n=1).
**Conclusions**
Most children undergoing BE and/or BM oral desensitization achieved maintenance. Reasons for discontinuation included dose-related allergic symptoms, especially with BM. Future studies optimizing protocols for BM and BE oral desensitization are encouraged.

BAKED EGG AND BAKED MILK ORAL DESENSITIZATION OUTCOMES IN A PEDIATRIC COHORT

Consortium for Graduate Medical Education 13th Annual Resident Research Day

Icahn School of Medicine at Mount Sinai

COVID-19 VACCINE ACCEPTANCE IN PREGNANCY

FAST Exam Education for Pediatric Residents in the Pediatric Emergency Department

Frequency of Appropriate Post Laceration Repair Instructions In An Academic Pediatric Emergency Department

PATIENT AGITATION AND VIOLENCE IN MED-SURG UNITS AND EMERGENCY DEPARTMENT AT BRONXCARE HOSPITAL, PRE AND POST COVID-19 PANDEMIC; A RETROSPECTIVE CHART REVIEW