The volume of experimentation conducted in support of Active Pharmaceutical Ingredient (API) development, from the time of compound identification to the time of commercialization, is extensive. In the high throughput screening group our goals are two-fold: generating fundamental data as well as mapping potential reaction space. One recent focus around evolving workflows for measurement of solubility, physical form identification/characterization and partition coefficients measurements will be shared here. Utilizing high throughput methods and extracting maximal data from each experiment enhances our ability to support fast, informed decision making.

Generation of rich datasets for chemistry explored in pharmaceutical route development

ACS Spring 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.