In recent years, new developments in Size Exclusion Chromatography (SEC) have resulted in the introduction of Ultra High-Performance Liquid Chromatography (UHPLC or UPLC®) for polymer applications. Waters ACQUITY Advanced Polymer Chromatography (APC™) is a breakthrough technology that provides SEC analyses of polymeric materials with higher-resolution and higher-speed than conventional SEC. The new APC technology involves the use of high efficiency separation columns and a low dispersion flow path, resulting in: High resolution analysis Reduced time Reduced solvent consumption Reduced sample concentration Quick mobile phase changeover The APC system generates extremely precise, reproducible molecular weight information through conventional calibration. To obtain comprehensive knowledge of the polymers under analysis, it is necessary to combine the high-resolution APC system with additional advanced detectors. The combination of the Waters APC system with the Malvern Panalytical OMNISEC REVEAL, containing refractive index (RI), UV-Vis photodiode array (UV), light scattering (LS), and differential viscometry detectors, greatly broadens the information attainable from a SEC analysis. Using OMNISEC REVEAL the sample under analysis can now be fully characterized in terms of: Absolute molecular weight: without the need for column calibration Molecular weight distribution Size: hydrodynamic radius across the sample’s entire molecular weight range Structure: Mark-Houwink parameters Composition This presentation will discuss the benefits of characterizing polymers by a Waters ACQUITY APC combined with the Malvern Panalytical OMNISEC REVEAL multi-detector system.

Unlocking polymers: Combining advanced polymer chromatography with advanced multi-detection for complete high-resolution polymer characterization

ACS Spring 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.