Recent research and development have revealed that certain vitamin compound and derivatives, including phylloquinone (VK1), menatetrenone (VK2), menadione (VK3) menadiol diacetate (VK4), menadione sodium bisulfite (MSB, soluble VK3 derivative), riboflavin (RF, VB2), and flavin mononucleotide (FMN, VB2 derivative), are photo-active and can produce reactive oxygen species (ROS) under daylight or UVA illuminations. These agents are basically edible and safe for applications for food contact materials without showing any biocidal functions under dark. Their photoactive mechanisms and produced reactive oxygen species, which are the biocides in the systems, are different, thus, their applications may need varied environment to provide the desired light-induced biocidal functions. In addition, the ROS are super reactive and only exist in very short time after generation. These features make the applications of the agents in various antibacterial surfaces and materials uniquely different and challenging. In this presentation, the photo-induced biocidal mechanisms of representative compounds are discussed with computational modeling and experimental results. Creative applications of the agents in food preservation and reduction of biofilms under varied lighting conditions will be illustrated.

Vitamin derivatives as effective light controlled biocidal agents for food contact surfaces

ACS Spring 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.