Tissue engineering and regenerative medicine have the potential to transform the way we treat the human body. However, the ability to recapitulate the 3D environment of tissues and cells remains a major bottleneck for the field. From mimicking the complex extracelluar matrix (ECM) to positioning cells in the right place at the right time, the spatiotemporal control of cells and their environment remain crucial for tissue growth. Our lab designs new dynamic materials to enable customizable and life-like tissue constructs with cells. Via (macro)molecular design, we can control the rheological properties of hydrogels and control the cell-biomaterial interactions across stiffness and relaxation timescales using both dynamic covalent Schiff base formation and supramolecular interactions. By combining the power of macromolecular design, with cell culture, and biofacbrication technologies, we aim to push forward our ability to create more life-like tissue engineering constructs.

Dynamic hydrogels for tissue engineering: From molecular design to 3D printing

ACS Spring 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.