In a three-hour organic chemistry laboratory period, it is difficult to expose students to any synthesis that requires more than one step. The alternative is to carry out a two, three, or even four step syntheses over the course of two, three, or four laboratory periods. One drawback to a multiple lab period approach is the difficulty in aligning reaction coverage in lecture with the reactions they cover in in the lab. Seldom does the reaction order in a multistep synthesis line up perfectly with that same order in lecture. This poster demonstrates a three-reaction sequence that mirrors a typical coverage of the end of organic II lecture.This requires students to be responsible for products over multiple lab periods and allows a discussion of a percent yeild for a reaction versus a overall yeild for a multistep synthesis. This approach would also be a greener and less costly method since new starting materials would only need to be purchased for the first step of the synthesis.

Novel multistep synthesis for undergraduate organic laboratory

ACS Spring 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.