In 2018, we published our preliminary results on the cationic alkynyl-Heck reaction between aryl triflates and alkynes to access substituted allenes. Since then, we have pursued studies to understand the mechanistic underpinnings of this reaction to catalyze the discovery of new approaches to allenes. In particular, our focus has been on the development of novel Pd(0)-based catalysts that have been rationally designed to promote the alkynyl Heck reaction with additional aryl (pseudo)halides. The impact of this work includes providing new approaches to substituted allenes, the creation of novel Pd(0) catalysts, and mechanistic details that will further spur additional discoveries in the synthesis of allenes. What will be reported here is our latest efforts in all three of these areas.

Synthetic and mechanistic studies towards catalytic syntheses of allenes

ACS Spring 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.