There is an increased risk for burn injuries associated with home oxygen therapy of patients with chronic
obstructive pulmonary disease (COPD) since 10% to 50% of these patients continue to smoke. Enzymatic
eschar removal of facial burns is gaining popularity but intubation of this specific patient group often
leads to prolonged weaning and can require tracheostomy. This study dealt with the question if enzymatic
debridement in these patients can also be performed in analgosedation. A selective review of the literature
regarding burn trauma associated with home oxygen use in patients with COPD was performed, as well as
a retrospective analysis of all patients with burn injuries associated with home oxygen use and COPD that
were admitted to the study clinic. In the literature, 1746 patients with burns associated with home oxygen
use are described, but none of them received enzymatic debridement. In this study, 17 patients were included.
All three patients in this study with facial full-thickness burn injuries received enzymatic debridement. The
mortality rate in this cohort was 17.6% (3/17). Up to date, there is limited experience performing regional
anesthesia debridement in patients with COPD. This is the first manuscript describing the use of enzymatic
debridement in patients with COPD and home oxygen therapy. We could confirm other studies that intubation
of these patients leads to prolonged ventilation hours and increases the probability for poor prognosis.
Therefore, we described the treatment of enzymatic debridement in analgosedation without intubation.

P.027 To intubate, or not to intubate, that is the question: Nexobrid treatment for burn injuries in patients with Chronic Obstructive Pulmonary Disease and Home Oxygen Therapy

Dear friends and colleagues,

We will be pleased to welcome you in Turin (Italy) for the 19th European Burns Association´s Congress in 2022. Italy is honored to hold the meeting of the European Burns Association for the second time, after Verona in 1995. Turin is easily reachable from everywhere in Europe, either travelling by car, train or choosing flight connections. During the meeting, held in the renewed industrial center of the main Italian historical automotive factory (i.e. Lingotto-FIAT), we will meet international burn specialists, focusing on standards of care, progresses in burn treatment, strategies to face disaster situations, with a special attention to education of younger colleagues. However, in your spare time, you might enjoy the sweet days of Italian late summer, simply wandering in the green parks and gardens along the two rivers which cross the city, or you might decide to discover the numerous art galleries, churches, palaces, libraries, walking across elegant squares and large boulevards, passing through centuries of art and history; finally, you may choose to immerse yourself in some of the most exciting museum experiences, such as the Cinema Museum and the Turin’s Egyptian museum.

Looking forward to seeing you all in Turin for the 19th European Association´s Congress in 2022!
Maurizio Stella, Congress President, Turin Burn Centre