A NOVEL TECHNOLOGY – ENZYMATIC DEBRIDEMENT – NEXOBRID IN COMBINATION WITH HY TISSUE MICROGRAFTS
TASKOV Panche 1,2, NEMES Mircea 1, CRAINICEANU Zorin 1,2
1. Plastic and Reconstructive Surgery Clinic – Casa Austria,
Emergency County Hospital “Pius Branzeu” Timisoara, Romania
2. University of Medicine and Pharmacy “Victor Babes” Timisoara, Romania
Introduction:
We present a novel concept consisting of enzymatic debridement - Nexobrid of deep partial-thickness and full-thickness burns in combination with Hy Tissue Micrografting technique using autologous micrografts and "smart" dressings, avoiding SOC treatment using tangential excision and split thickness skin graft (STSG) coverage.
Material and methods:
In a retrospective case study, 3 patients (1st 85% TBSA, 2nd 45% TBSA, 3rd 15% TBSA)
with deep partial-thickness and full-thickness burns were treated with enzymatic debridement and autologous cell therapy.
Our novel tehnique was applied to up to 5% TBSA.
Other injuries were treated with enzymatic debridement, surgical excision and skin grafting - split thickness skin graft (STSG) and MEEK micrograft coverage.
Results:
All three patients in areas treated with our new technique did not require additional surgery and coverage.
In less than 2 weeks the lesions completely epithelized.
Conclusion:
The use of selective enzymatic debridement in combination with hy tissue technique is a regenerative technique of the future, in order to reduce the need for grafting using its own donor area or allografts / xenografts currently unavailable nationally.
This technique will show its efficacy when higher standardization and experience is achieved.
We observed a reduced healing period and length of hospital stay,
improvement in time to full epithelialisation,
areas treated did not require additional surgery and coverage,
the elasticity, quality of and the aesthetic aspect of the scars is clearly superior to
scar quality in comparison with traditional excision and skin grafting.
Keywords:
Enzymatic debridement, Nexobrid, Micrografting technique, Hy Tissue

**A NOVEL TECHNOLOGY – ENZYMATIC DEBRIDEMENT – NEXOBRID IN COMBINATION WITH HY TISSUE MICROGRAFTS**
TASKOV Panche 1,2, NEMES Mircea 1, CRAINICEANU Zorin 1,2
1. Plastic and Reconstructive Surgery Clinic – Casa Austria,
Emergency County Hospital “Pius Branzeu” Timisoara, Romania
2. University of Medicine and Pharmacy “Victor Babes” Timisoara, Romania
**Introduction:**
We present a novel concept consisting of enzymatic debridement - Nexobrid of deep partial-thickness and full-thickness burns in combination with Hy Tissue Micrografting technique using autologous micrografts and "smart" dressings, avoiding SOC treatment using tangential excision and split thickness skin graft (STSG) coverage.
**Material and methods:**
In a retrospective case study, 3 patients (1st 85% TBSA, 2nd 45% TBSA, 3rd 15% TBSA)
with deep partial-thickness and full-thickness burns were treated with enzymatic debridement and autologous cell therapy.
Our novel tehnique was applied to up to 5% TBSA.
Other injuries were treated with enzymatic debridement, surgical excision and skin grafting - split thickness skin graft (STSG) and MEEK micrograft coverage.
**Results:**
All three patients in areas treated with our new technique did not require additional surgery and coverage.
In less than 2 weeks the lesions completely epithelized.
**Conclusion:**
The use of selective enzymatic debridement in combination with hy tissue technique is a regenerative technique of the future, in order to reduce the need for grafting using its own donor area or allografts / xenografts currently unavailable nationally.
This technique will show its efficacy when higher standardization and experience is achieved.
We observed a reduced healing period and length of hospital stay,
improvement in time to full epithelialisation,
areas treated did not require additional surgery and coverage,
the elasticity, quality of and the aesthetic aspect of the scars is clearly superior to
scar quality in comparison with traditional excision and skin grafting.
**Keywords:**
Enzymatic debridement, Nexobrid, Micrografting technique, Hy Tissue

P.035 A NOVEL TECHNOLOGY – ENZYMATIC DEBRIDEMENT – NEXOBRID IN COMBINATION WITH HY TISSUE MICROGRAFTS

Dear friends and colleagues,

We will be pleased to welcome you in Turin (Italy) for the 19th European Burns Association´s Congress in 2022. Italy is honored to hold the meeting of the European Burns Association for the second time, after Verona in 1995. Turin is easily reachable from everywhere in Europe, either travelling by car, train or choosing flight connections. During the meeting, held in the renewed industrial center of the main Italian historical automotive factory (i.e. Lingotto-FIAT), we will meet international burn specialists, focusing on standards of care, progresses in burn treatment, strategies to face disaster situations, with a special attention to education of younger colleagues. However, in your spare time, you might enjoy the sweet days of Italian late summer, simply wandering in the green parks and gardens along the two rivers which cross the city, or you might decide to discover the numerous art galleries, churches, palaces, libraries, walking across elegant squares and large boulevards, passing through centuries of art and history; finally, you may choose to immerse yourself in some of the most exciting museum experiences, such as the Cinema Museum and the Turin’s Egyptian museum.

Looking forward to seeing you all in Turin for the 19th European Association´s Congress in 2022!
Maurizio Stella, Congress President, Turin Burn Centre