The Use of Primatrix in Deep Burns Following Enzymatic Debridement: A Case series
Objective:Modern burn care requires assets and resources. The focus is on developing novel non-invasive treatment options that will benefit patients in the long run while also saving hospitals money. The goal of this study is to see how well our minimally invasive burn wound treatment technique works in patients who don't need intensive care.
Methods:A review of the patients' medical records was conducted retrospectively. Between January 2020 and January 2021, 52 patients of both sexes (>17 years old) with deep partial thickness (DPT) and full thickness (FT) burns, including burns of the extremities, were admitted. Within 24 hours of the injury, all of the patients received early enzymatic debridement (ED) (Nexobrid), which can also be used for escharotomy. All of the wounds were covered with Primatrix (PTX), a repair scaffold, after 48 hours. Both treatments were done at the patient's bedside, with prior analgesia-sedation. Patients were discharged to their homes as they awaited wound closure, with one weekly follow-up appointment planned.
Results: There were 52 patients in total, 35 of whom were males. The mean age was 55.4 (17 -81). Total body surface area (TBSA) was 13% (5-25).  Burn wounds were first diagnosed as 89% deep partial thickness (DPT) and 11% full thickness (FT) burns, including extremity burns. In comparison to the initial diagnosis, the post-ED did not indicate any FT burns area. For all patients, the demand for blood transfusions and the necessity for an operating room was none. After PTX application, all of the patients reported reduced pain. The average time until discharge was 13 (5-28) days, and the average follow-up in the outpatient clinic was every 7 days. The average period for wound closure was 7-14 days. None of the patients died, and none of them had any adverse reactions or complications.
Conclusion:The combined treatment strategy NXB+PTX can offer a minimal invasive modality of burn wound treatment, accelerate wound healing, and reduce hospitalization time in patients with non-severe comorbidities, providing greater comfort to patients and benefits to the healthcare system, according to our observation.

**The Use of Primatrix in Deep Burns Following Enzymatic Debridement: A Case series**
**Objective:**Modern burn care requires assets and resources. The focus is on developing novel non-invasive treatment options that will benefit patients in the long run while also saving hospitals money. The goal of this study is to see how well our minimally invasive burn wound treatment technique works in patients who don't need intensive care.
**Methods:**A review of the patients' medical records was conducted retrospectively. Between January 2020 and January 2021, 52 patients of both sexes (>17 years old) with deep partial thickness (DPT) and full thickness (FT) burns, including burns of the extremities, were admitted. Within 24 hours of the injury, all of the patients received early enzymatic debridement (ED) (Nexobrid), which can also be used for escharotomy. All of the wounds were covered with Primatrix (PTX), a repair scaffold, after 48 hours. Both treatments were done at the patient's bedside, with prior analgesia-sedation. Patients were discharged to their homes as they awaited wound closure, with one weekly follow-up appointment planned.
**Results:** There were 52 patients in total, 35 of whom were males. The mean age was 55.4 (17 -81). Total body surface area (TBSA) was 13% (5-25).  Burn wounds were first diagnosed as 89% deep partial thickness (DPT) and 11% full thickness (FT) burns, including extremity burns. In comparison to the initial diagnosis, the post-ED did not indicate any FT burns area. For all patients, the demand for blood transfusions and the necessity for an operating room was none. After PTX application, all of the patients reported reduced pain. The average time until discharge was 13 (5-28) days, and the average follow-up in the outpatient clinic was every 7 days. The average period for wound closure was 7-14 days. None of the patients died, and none of them had any adverse reactions or complications.
**Conclusion:**The combined treatment strategy NXB+PTX can offer a minimal invasive modality of burn wound treatment, accelerate wound healing, and reduce hospitalization time in patients with non-severe comorbidities, providing greater comfort to patients and benefits to the healthcare system, according to our observation.

P.158 The Use of Primatrix in Deep Burns Following Enzymatic Debridement: A Case series

Dear friends and colleagues,

We will be pleased to welcome you in Turin (Italy) for the 19th European Burns Association´s Congress in 2022. Italy is honored to hold the meeting of the European Burns Association for the second time, after Verona in 1995. Turin is easily reachable from everywhere in Europe, either travelling by car, train or choosing flight connections. During the meeting, held in the renewed industrial center of the main Italian historical automotive factory (i.e. Lingotto-FIAT), we will meet international burn specialists, focusing on standards of care, progresses in burn treatment, strategies to face disaster situations, with a special attention to education of younger colleagues. However, in your spare time, you might enjoy the sweet days of Italian late summer, simply wandering in the green parks and gardens along the two rivers which cross the city, or you might decide to discover the numerous art galleries, churches, palaces, libraries, walking across elegant squares and large boulevards, passing through centuries of art and history; finally, you may choose to immerse yourself in some of the most exciting museum experiences, such as the Cinema Museum and the Turin’s Egyptian museum.

Looking forward to seeing you all in Turin for the 19th European Association´s Congress in 2022!
Maurizio Stella, Congress President, Turin Burn Centre