We present the case of a 71-year-old female patient who was admitted to our clinic for the presence of erythematous-petechial and vesiculo-bullous lesions, which occur spontaneously or after minor trauma, disseminated throughout the body, with an evolution of over 3 years. Histopathological examinations were not specific to epidermolysis bullosa, although the clinical examination was highly suggestive. After therapeutic failure with Colchicine and Dapsone, it was decided to start treatment with Medrol with a favorable outcome after one month of treatment. Although the diagnostic criteria are not defined the clinical aspects and the evolution under corticosteroid treatment support the diagnosis of epidermolysis bullosa acquisita. Renal biopsy is performed showing proximal tubulopathy with lambda light monoclonal chains. Considering all the investigations, the diagnosis of monoclonal gammopathy was made and the patient is to be treated with Lenalidomide plus Dexamethasone.

ESDR069 - EBA – a dermatological challenge. Clinical case

The scientific meeting of the European Society for Dermatological Research (ESDR) is held yearly, usually in September. With an international attendance of more than 1000 skin scientists from around the globe, the four-day event includes short oral presentations from peer-reviewed abstracts, keynote lectures from international experts, sponsored symposia, satellite programs, educational events as well as an important focus on posters, networking and building collaborations amongst scientists. For more information about this year’s meeting visit our website.