A patient survey that aimed to best identify the unmet needs in brachioradial pruritus (BRP) was conducted from 10/2021 to 04/2022 in English online. The survey, created in collaboration with BRP patients and experts in BRP, included 36 questions focusing on the most significant elements of living with BRP: journey to diagnosis, severity and frequency of symptoms, treatment history, and impact on quality of life. 545 anonymous respondents worldwide participated in the survey, with 322 having reported a confirmed BRP diagnosis by a physician. The majority of patients were 50-69 years old (62%), female (94%), and in the US (74%). Data showed it took at least three years since first experiencing BRP symptoms for 43% of patients to receive a correct diagnosis, and 52% visited at least three different physicians before the diagnosis was made. Misdiagnosis [other diagnoses prior to final diagnosis of BRP] was common (in 39%). Most (85%) patients had severe itch (itch score ≥7) in their last episode, and 88% had visible scratch marks or bleeding. 78% suffer from itch at least three months per year, of which 28% suffer for over nine months per year. Patients often tried several drug treatments (mean >4) for itch, with the most helpful receiving only 21% of responses. Sleep quality is highly affected in 77% of patients, and 71% use ice packs at night. For the vast majority (92%), their itch frustrates them often or all the time. These data show that a substantial proportion of BRP patients endure a difficult path to diagnosis, suffer from severe itch for the majority of the year, lack a clear treatment option, and experience a highly negative impact on their quality of life. These results emphasize the need to increase awareness of BRP, address patients' unmet needs, and develop effective treatments for BRP.

ESDR118 - High unmet medical need in brachioradial pruritus: results from a large patient survey

The scientific meeting of the European Society for Dermatological Research (ESDR) is held yearly, usually in September. With an international attendance of more than 1000 skin scientists from around the globe, the four-day event includes short oral presentations from peer-reviewed abstracts, keynote lectures from international experts, sponsored symposia, satellite programs, educational events as well as an important focus on posters, networking and building collaborations amongst scientists. For more information about this year’s meeting visit our website.