The previous studies have shown the efficacy of PWS treatment with large spot 532 nm laser, with median maximal improvement achieved during treatment (GCEmax) ranging from 50% to 70%. [We aimed to] assess the efficacy of PWS treatment with the use of a large spot 532 nm laser over a prolonged period. Sixty-four Caucasian patients aged 6 to 59 treated with 2 to 30 laser sessions were included in this study. Patients had 3D photography performed before and after treatment with a 532 nm Nd:YAG laser with large spot and contact cooling. An objective analysis of percentage improvement based on a 3D digital assessment of combined colour and area improvement (global clearance effect [GCE]) were performed. In addition to a retrospective review, we performed a prospective treatment evaluation in patients with a treatment interruption greater than 3 years. The median maximal improvement achieved during the treatment (GCEmax) was 59.1 % (GCE59). The first two laser procedures had a median maximal improvement of 28.46%, while the first 5,10,15 and 20 laser procedures had respectively 45.48%, 56.57%, 56.97% and 56.96% total maximal improvements. The procedures have been divided into time groups, based on time passed in-between procedures, and the relation between time-group and negative total clearance improvements has been found. Analysis indicates that large spot 532 nm laser is highly effective in the treatment of PWS. Further analysis proofs the first five laser procedures have higher efficacy and improvements start plateauing around the 10th visit. The established correlation between time groups and the efficacy of treatment could be explained by the exacerbating of PWS over time, indicating further bi-yearly treatment is needed to counteract deterioration.

ESDR163 - Induction and maintainance treatment of Port Wine Stains with large spot 532nm laser

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