SARS-CoV-2 infection has been associated with the reactivation of infection with varicella zoster virus. This is a potential observation of a local susceptibility of the skin in areas of vesicle formation. This paper explores the cutaneous manifestations that have been linked to the SARS-CoV-2 virus, their infectious risk, as well as potential confounding factors. An isotopic response may be occurring due to the occurrence of an immunocompromised district incited by sustained inflammation mediated by inflammatory cytokines. The SARS-CoV-2 virus, which is causing the present worldwide pandemic, has been linked to a variety of dermatological conditions, including pseudochilblain, vesicular, urticarial, maculopapular, and livedo/necrosis-like lesions. COVID-19-related enantemas or exantemas may arouse suspicion of SARS-CoV-2 infection, although they can also appear in other viral illnesses such as rubella or measles. The potentiating element that facilitates the activation of latent viral infections could be the localized susceptibility generated by SARS-CoV-2 symptoms. These occurrences could be explained by a local susceptibility of previously damaged skin, which underpins concepts like the Wolf isotopic reaction or/and Koebner phenomenon type V.

ESDR168 - New considerations regarding vesicular rashes associated with SARS-CoV2 infection and Koebner phenomenon

The scientific meeting of the European Society for Dermatological Research (ESDR) is held yearly, usually in September. With an international attendance of more than 1000 skin scientists from around the globe, the four-day event includes short oral presentations from peer-reviewed abstracts, keynote lectures from international experts, sponsored symposia, satellite programs, educational events as well as an important focus on posters, networking and building collaborations amongst scientists. For more information about this year’s meeting visit our website.