Mice on high fat (HF) diets were fed fermented loquat (Eriobotrya japonica) leaves (FLL) to evaluate their antiobesity properties because of their use to treat inflammation and diabetes in traditional medicines.  FLL were either purchased from a local herbalist or prepared in our laboratory.  C57Bl/6J mice were fed high fat (HF, 48% fat calories) diets for 30 d.  HF diets supplemented with 20% FLL or the ethanol extracts equivalent of 20% FLL (4.4 g/100 g diet) reduced body weight gain. 20% FLL or its ethanol extract also reduced adipose weight but not liver weight or blood glucose by the glucose tolerance test (GTT).  20% FLL reduced ghrelin and GLP-1, and 10% FLL reduced leptin, biomarkers for diabetes.  Compared to acarbose FLL extracts had no α-Amylase or  glucosidase inhibitory properties supporting the observation the GTT values. This study suggests that FLL has potential to reduce physiological characteristics of obesity related metabolic dysfunction.

Antiobesity properties of fermented loquat (Eriobotrya japonica) leaf teas in vivo and invitro

Fall 2022 abstracts, posters, and presentations will launch in mid-September.

ACS Fall 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.