In honor of Prof. H. B. Schlegel’s career achievements we present here the road that has taken us from the study of potential energy surfaces to cancer research. As many authors have stated the study of potential energy surfaces have provided critical insight into the energetics of an impressive number of chemical reactions. In our pursuit of studying large biological systems we have relied on the use of complementary computational techniques to gain an understanding of diseases such as cancer. This endeavor has taken us to consider methods where 3-dimentional molecular description need to be collapsed to 1-dimention. In this talk we describe how RNA sequencing can be used and it is currently being used in the genomic understanding of multiple types of cancer. Our aim is to introduce the use of RNA sequencing in the clinical prognosis of kidney and other cancers. The Memorial Sloan Kettering Cancer Center (MSKCC) prognostic score is based on clinical parameters. We showed that by introducing genomics we improve prognostication compared to the MSKCC standalone score.

From potential energy surfaces to cancer research

Fall 2022 abstracts, posters, and presentations will launch in mid-September.

ACS Fall 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.