The past few years have witnessed an increasing interest towards replacing and augmenting sutures with tissue adhesives. The application of tissue adhesive results in increased rate of wound healing without excessive tissue deformation. This requires tissue adhesive to have high initial tack and the ability to bond rapidly to living tissue forming a permeable flexible bond. Furthermore, the strength of the bond should be sufficiently high to cause tissue failure before bond failure. Moreover, the degradation products of the adhesive should be safe and biocompatible. Although a number of tissue adhesives based on different chemistries including polyurethanes have been investigated but none of them have gained wide acceptance as they failed to meet one or other of the aforementioned requirements. In this study, we present our efforts towards developing novel absorbable tissue adhesives that incorporate all the properties inherent to a tissue adhesive

Absorbable polyurethane based tissue adhesives

Fall 2022 abstracts, posters, and presentations will launch in mid-September.

ACS Fall 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.