Optofluidic platforms have manifold possible applications as lab-on-chip or organ-on-chip systems for cell, bio- or environmental-analytics as well as pharmaceutical research and diagnostics. Applications of an optofluidic platform in reflection geometry for label-free infrared (IR) microscopic submonolayer-sensing (detection limit of about 0.03 nmol/cm2) are discussed. The platform based on metallic island enhancement substrates and user-defined microfluidic chips is extendable for combinatorial IR and Raman spectroscopic applications. As examples the adsorption behavior of self assembling monolayers of the tripeptide glutathione (GSH) and of streptavidin molecules on a biotinylated surface are investigated. (temporal resolution in the minute range)

Infrared microfluidics for monitoring of molecular adsorption

Fall 2022 abstracts, posters, and presentations will launch in mid-September.

ACS Fall 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.