Charged (bio)macromolecules exhibit rich phase behavior with the formation of liquid coacervates, viscoelastic gels, fibrils, and solid precipitates all observed both in vitro and in living cells. Of particular interest, is the multi-component phase separation driven by oppositely charged polyelectrolytes (e.g. peptides, proteins, and nucleic acids). We will describe our progress towards engineering polyelectrolyte complexation and phase separation of proteins of interest in cellular environments.

Protein-based polyelectrolyte complexes

Fall 2022 abstracts, posters, and presentations will launch in mid-September.

ACS Fall 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.