<br/>Many problems in modern materials chemistry require interfaces with highly structured chemical environments at near-molecular scales – ranging from nanoelectronics to ligand clustering in biology. For over a century, lipids have provided a powerful toolkit for controlling nanoscale interface chemistry, both for biology and for synthetic materials. Here, we describe the powerful chemical impacts of amphiphilic striped phases, which can be assembled on graphite, MoS<sub>2</sub>, and other 2D materials. In these monolayers, the alkyl chain orients parallel to the substrate, producing an interface that resembles a repeating cross-section of a lipid bilayer. These unusual molecular layer structures provide surprisingly robust and scalable nm-resolution chemical patterning, which can direct further material assembly. Recently, we have also demonstrated that these patterns can be transferred to soft, amorphous materials including PDMS, creating new opportunities for nanostructured material design. We will discuss the relationship between structure, reactivity and assembly in the molecular template layer, as well as applications of the templates in directing the assembly of inorganic nanocrystals and in designed cell scaffolds for regenerative medicine.

To flatland and back again: Lipid striped phases on graphite as a foundation for nanostructured material design

Fall 2022 abstracts, posters, and presentations will launch in mid-September.

ACS Fall 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.