The United States Environmental Protection Agency’s (U.S. EPA) Office of Pesticide Programs (OPP) regulates the use of all pesticide chemicals.  Numerous toxicity studies using laboratory animals are required for pesticide registration; however, regulatory statutes provide the EPA with the flexibility to modify the actual data and studies required on an individual basis.  This includes granting waivers for existing data requirements and utilization of bridging approaches on a case-by-case basis.  Additionally, the Agency may use data from alternative methods and strategies to satisfy data requirements.  The EPA’s strategy to reduce animal testing relies heavily on the development and implementation of new approach methodologies (NAMs).  NAMs have been adopted as a broadly descriptive reference to any non-animal technology, methodology, approach, or combination thereof that can be used to provide information on chemical hazard and risk assessment.  Strategies using non-traditional test species may also be considered NAMs. This presentation will discuss the progress OPP has made towards reducing its reliance on animal studies for risk assessment and adopting NAMs.

Efforts to reduce reliance on animal studies to support pesticide registrations

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ACS Fall 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.