Developing nonenzymatic chemistry that is non-toxic to microbial organisms creates the potential to integrate synthetic chemistry with metabolism and offer new remediation strategies. Nitro aromatic compounds contaminate groundwater can be converted into less environmentally persistant compounds by reduction to the aniline derivative. The reduction of substituted aryl nitro groups using Pd/C and ammonium formate in biological media under physiological conditions (neutral pH, moderate temperature, and ambient pressure) is reported for a range of aromatic nitro compounds. The relative toxicities of each reaction component separate and together were tested against bacteria to determine and develop biocompatibility.

Non-enzymatic nitro reduction in biological media at physiological conditions

Fall 2022 abstracts, posters, and presentations will launch in mid-September.

ACS Fall 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.