Iron carbonyl chemistry is relevant to elucidating the biosyntheses and function of the hydrogenase enzymes. The lecture will survey progress including manipulations of the active site through artificial maturation. Specifically, the preparation, use of [M2[(SCH2)2X](CN)2(CO)4]2- including authentic cofactors (M = Fe, X = NH), isotopically labelled cofactors (57Fe2[(S13C2H2)2NH]), and semi-artificial but isosteric cofactors (M = Ru). Similar strategies have been applied to the elucidating the potential biosynthetic significance of [Fe(cysteinate)(CN)(CO)2]- and [Fe2(SH)2(CN)2(CO)4]2-. The lecture will describe the utility of some classical reagents such as Collman's Na2Fe(CO)4 and Ellis's [Fe(anthracene)2]-.

Synthesis in service of bio-organoiron chemistry

Fall 2022 abstracts, posters, and presentations will launch in mid-September.

ACS Fall 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.