The use of meldonium (2-(2-Carboxylato-ethyl)-1,1,1-trimethylhydrazinium) and trimetazidine (1-(2,3,4-trimethoxybenzyl)piperazine) by Olympic athletes to improve their athletic performance has become a topic of debate in recent years. Debate about these performance enhancing drugs (PEDs) centers on the safety of their use by otherwise healthy athletes and whether these PEDS are actually enhancing athletic achievement. This study looks at the historical development of meldonium and trimetazidine, the timeframe for their use as PEDs, and development of analytical techniques for their detection. In addition, the use of the study findings for case studies in a quantitative analysis or biochemistry course will be discussed.

Investigating meldonium and trimetazidine as performance enhancing drugs by olympic athletes

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ACS Fall 2022

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