To determine whether bioconversion of whey and polyphenol-rich citrus pomace with kefir lactic acid bacteria potentiates anti-obesogenic bioactivities, C57BL/6J mice were fed a high-fat diet (HFD) with oral administration of saline (CON), cheese whey (WHE), citrus pomace extract (CPX), kefir lactic acid bacteria (LAB), and bioconversion product of citrus pomace and whey (CPB) for 5 weeks. Compared to the CON group, the CPB group showed significantly decreased body weight gain, adipose tissue weight/body weight ratio, diameter of adipocytes, and increased gene expression related to energy metabolism in adipose tissue (<i>p</i> &lt; 0.05). Interestingly, the abundance of gut microbiota related to obesity was significantly affected following CPB compared to CON. There is a significant correlation between obesogenic biomarkers and abundance of gut microbiota. In conclusion, kefir LAB derived bioconversion of whey and citrus pomace may be effectively useful to combat obesity and obesity-related diseases.

Kefir lactic acid bacteria derived bioconversion of citrus pomace and whey and high-fat diet-induced obesity

Fall 2022 abstracts, posters, and presentations will launch in mid-September.

ACS Fall 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.