Machine Learning (ML) and Digital Engineering (DE) are at the heart of today's different industries, ranging from advanced manufacturing to biomedical systems to resilient ecosystems, civil infrastructures, smart cities, and healthcare. They have become indispensable for solving complex problems in science, engineering, and technology development. The purpose of the MMLDE-CSET 2023 conference is to facilitate the transition of ML and DE from fundamental research to mainstream fields and technologies through advanced data science, mechanistic methods, and computational technologies. This 3-day conference features technical tracks of emerging ML-DE fields and applications, special public lectures, short courses, and demonstrations. The conference will be held in a hybrid format, featuring both on-site and virtual sessions.

2nd IACM Mechanistic Machine Learning and Digital Engineering for Computational Science Engineering and Technology