Direct and selective functionalization of C-H and C=C bonds has a great potential towards generating a plethora of high value chemical compounds from readily available hydrocarbons. Our work seeks to produce and expand a library of catalysts used for oxygen or nitrogen group insertion chemistry by utilizing first row transition metals. Macrocyclic ligands and their metal complexes have been synthesized and explored as catalysts, as they are thermodynamically more stable and oxidatively robust. Recent work has involved frameworks with the end goal of N4 coordination of the desired transition metals. Tetraaza macrocyclic chiral ligands have been synthesized and are currently being further explored as chelating agents of metal catalysts for nitrene- transfer chemistry vis-à-vis C–H and C=C bonds. A series of tetraamido and tetraaza macrocyclic ligands have been synthesized and metallated with suitable Cu, Fe, Co and Mn precursors, and further employed for the aziridination of olefins and amination of C–H bonds.

Synthesis of first row transition metal complexes supported by tetraaza and tetraamido macrocyclic ligands: Potential catalysts in nitrene transfer chemistry

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