Over 100 years ago Banting, Best, Collip and Macleod discovered a method to extract insulin from animal pancreases in a breakthrough discovery. As great an accomplishment as this was, the ability to provide a reliable and consistent supply of this life-giving medicine was at times elusive. Through the scientific perseverance at Eli Lilly and Company the goal of having a reliable supply of insulin with consistent quality became a reality for patients around the world. Technological advances, such as the advent of recombinant DNA technology, have evolved insulin manufacturing from the initial processes purifying bovine and porcine derived insulin, to sophisticated and high throughput processes capable of delivering highly pure human insulin and analogs. This historical perspective will be highlighted within the presentation and provides a backdrop for the cutting-edge science being presented within this symposium.

100 Years of insulin innovation: A historical perspective

Where thousands of chemistry professionals meet to share ideas and advance scientific and technical knowledge. Spring 2023 abstracts, posters, and presentations will launch at the end of March.

ACS Spring 2023

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.