Nosocomial or hospital-acquired infections (HAIs) are responsible for increased morbidity and mortality rates in hospitals and care facilities. Although numerous guidelines and policies on cleaning and disinfection exist for preventing nosocomial infections, strict compliance remains challenging in understaffed facilities. The prevalence of drug-resistant organisms often entails excessive use of chemical disinfectants that could have undesired residual toxicities. The HiNW light disinfection technology employs a combination of intense light to disinfect surfaces. It works by generating reactive oxygen species that damages the plasma membrane resulting in cell death. They also react with other biomolecules (e.g., proteins and nucleic acid) to diminish the viability of the microbes. Indeed, better than 4 log reduction (99.99%) reduction in <i>P. aeruginosa</i> and multidrug-resistant <i>P. aeruginosa</i> (MRPA) was demonstrated.

Bactericidal mechanisms of pulsed and intermittent lighting from a high-intensity, narrow-wavelength (HiNW) light disinfection device

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ACS Spring 2023

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.