Heparin is a negatively charged polysaccharide that can be used as an anticoagulant drug for pharmaceutical purposes. It can be found in the mucosal tissues of porcine intestines. The prevalent issue in extracting heparin is the quantity and quality that comes from the intestines, which entails that the heparin adsorption efficiency of resins needs to be evaluated. The negative charge of heparin is used for its extraction. Spherical bead resins more specifically anion exchange resins are used to extract heparin like Amberlite, a commercial resin. This experiment aims to find a more efficient adsorbent than Amberlite to extract heparin from the porcine mucosa. The factors that affect a resin are its porosity, hydrophilicity/ hydrophobicity control, and degree of cross-linking. Also, the larger the surface area the more likely for the heparin to be absorbed and the resin needs to be non-toxic. Therefore, we will be utilizing functionalized biochar to observe if it is a better adsorbent than commercial resins.

Functionalized biochar for heparin recovery

Where thousands of chemistry professionals meet to share ideas and advance scientific and technical knowledge. Spring 2023 abstracts, posters, and presentations will launch at the end of March.

ACS Spring 2023

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.