This poster will disclose a strategy for the generation of lactam derivatives via a Pd(II) catalytic reaction by using Mo(CO)6 as a CO source. Unprotected secondary amines are converted to tertiary lactams as a desired product under these conditions. Preliminary mechanistic studies will also be discussed, as well as applications towards the synthesis of pharmaceuticals.

Unsaturated lactams via C–H activation using Pd(II

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ACS Spring 2023

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