Natural products provide a rich source of medicinal compounds. Alafia species have yielded several bioactive compounds. For example, the extracts from the bark of Alafia multiflora are traditionally used for wound treatment. This study focused on isolation and characterization of compounds from Alafia multiflora. Extraction of crude compounds was carried out on dried, ground stem bark using hexane, ethyl acetate, dichloromethane and methanol and water. The crude compounds were screened for bioactivity, separated by chromatography and characterized using nuclear magnetic resonance, infrared spectroscopy, UV-vis spectroscopy and liquid chromatography-mass spectrometry techniques. In addition, antimicrobial screening was carried out to determine the potential of the isolated compounds to inhibit bacterial growth and antiproliferative activity against cancer cell lines.

Isolation, characterization, and bioactivity screening of compounds from the stem bark of <i>Alafia multiflora</i>

Where thousands of chemistry professionals meet to share ideas and advance scientific and technical knowledge. Spring 2023 abstracts, posters, and presentations will launch at the end of March.

ACS Spring 2023

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.

Isolation, characterization, and bioactivity screening of compounds from the stem bark of Alafia multiflora