The 1,2,3-triazole-modified ruthenium carbene complexes (TA-Ru) were designed and synthesized as a new class of Grubbs catalysts, achieving effective challenging olefin metathesis at high temperature. Previously reported N-tethered Ru-carbene complexes suffers from rapid cis/trans isomerization, leading to the significantly reduced catalyst reactivity. This new triazole-Ru complexes hold the active trans-dichloro conformation even at 80 <sup>o</sup>C. The significantly improved thermal stability allows the TA-Ru serves as effective catalysts for challenging substrates over the original Grubbs II and Hoveyda-Grubbs catalysts, offering a new system for cross-metathesis (CM), ring-closing metathesis (RCM) and ring-opening metathesis polymerization (ROMP) with improved reactivity and efficiency.

Achieving olefin metathesis at elevated temperature with triazole modified Grubbs catalysts: Balanced reactivity and stability

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