<br/>Our research focuses on next-generation sequence-defined materials inspired by proteins. We combine new synthetic chemistry and Suzuki catalysis with computer-aided design to achieve novel three-dimensional nanostructures able to mimic the functions of protein cavities. In this poster presentation, I am going to discuss the basic design philosophy and provide examples for the scalable synthesis of some of the first molecular springs with tunable spring constants, which do not unfold. We use a Suzuki coupling for the controlled synthesis of single-handed macromolecular springs for which we show that increased helix diameter leads to increased flexibility. We are additionally exploring a new synthesis that uses Suzuki catalysis combined with a novel synthetic method for hydrolytically stable molecular nanocages.

New applications of Suzuki catalysis for precision nanostructure synthesis

Where thousands of chemistry professionals meet to share ideas and advance scientific and technical knowledge. Spring 2023 abstracts, posters, and presentations will launch at the end of March.

ACS Spring 2023

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.