C-centered radicals mediated reactions are useful transformations in modern synthetic chemistry. The explorations of diverse carbon radical sources have remained a longstanding goal methodology development, with the aim to offer a wide assortment and to obtain selectivity in the generation of these open shell reactive species. As continues of our group’s effort in developing novel single-electron chemistry of aromatic N-oxides. Herein, we present a novel protocol with applying pyridine N-oxides as catalyst for photoinduced carbon radical generation from boronic acids. The developed method using readily available and facilely tunable pyridine N-oxides as catalyst for boronic acid activation is simple, robust and demonstrates broad applicability for alkylation, allylation, amination, and azidation reactions.

Photoinduced carbon radical generation from boronic acid catalyzed by pyridine N-oxides

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