As most chemical reactions require an excess of solvents, they create large amounts of waste. Thus, it is important to find ecofriendly alternatives to these processes. Mechanochemistry uses mechanical work to induce chemical reactions, without the need for solvents. This work examines the milling of chemically active sugars for various reactions. We find mechano-glycosylation and –mutarotation occurs with favorable product conversion, while mechano-acetylation requires optimization. These findings will be used to develop inexpensive, simple, and eco-friendly pathways for glycan reactions, which have applications in viral binding, detection, and research technology.

Study on mechanochemically induced chemical reactions

Where thousands of chemistry professionals meet to share ideas and advance scientific and technical knowledge. Spring 2023 abstracts, posters, and presentations will launch at the end of March.

ACS Spring 2023

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.