Heparin is a polysaccharide found in porcine intestinal mucosa that inhibits blood coagulation. Currently, resins like Amberlite FPA98 CI that are used commercially for heparin recovery are expensive and environmentally harmful. Finding alternative ways to recover heparin becomes increasingly more important to reduce cost, protect the environment, and to be easily manufacturable. The extraction and production of heparin from porcine intestinal mucosa by using functionalized materials would make a valuable pharmaceutical ingredient more readily available. This study analyzes the effects of diatomaceous earth-based materials on heparin recovery from aqueous solutions containing 1000 PPM of heparin. In addition, we examined the impact of various factors in the reclamation of heparin including pH and temperature.

Efficient heparin uptake by using the low-cost diatomaceous earth

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