A three-step synthesis was utilized to form alkynyl functionalized chalcone dibromides. The first step of the process was the synthesis of a chalcone from 4-iodobenzaldehyde and an acetophenone with various substituents. The second step was a green bromination reaction to form a chalcone dibromide. The third step involved a Sonogashira coupling reaction to form alkynyl functionalized chalcone dibromides. The products of the synthesis were confirmed with NMR and IR spectroscopy.

Functionalization of iodo-substituted chalcone dibromides

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