Palladium(II) complexes were synthesized by the reaction of (4,7-dichloro-1,10-phenanthroline)palladium(II) chloride and nitrogen-based ligands, including isonicotinamide, acetamide, imidazole, theophylline, and 4-pyradinecarbonitrile. In all complexes, the inner coordination sphere contains one 4,7-dichloro-1,10-phenanthroline as the ancillary ligand and at least one nitrogen-based ligand creating a distorted square planar geometry around the metal center. Infrared spectroscopy, <sup>1</sup>H NMR spectroscopy, and single-crystal X-ray diffraction were used to determine the structure of novel complexes. Cytotoxic activity against MCF-7 human breast cancer cells will be reported to establish the potential of these new complexes as antitumor drugs.

Cytotoxicity of novel palladium(II) complexes containing 4,7-dichloro-1,10-phenanthroline as ancillary ligand

Where thousands of chemistry professionals meet to share ideas and advance scientific and technical knowledge. Spring 2023 abstracts, posters, and presentations will launch at the end of March.

ACS Spring 2023

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.