Carbonyl-olefin metathesis (COM) is ring-closing carbon-carbon bond formation that provides access to cyclic alkenes. A popular method for mediating COM reactions is through Lewis acid catalysis; however, these catalysts require anhydrous conditions, which complicates setup. Phosphoramides are up and coming in organocatalysis and have been shown to catalyze COM reactions without the need for anhydrous conditions. Herein, we report the synthesis and characterization of phosphoramide catalysts tested on a model substrate. These results will further guide Brønsted-Lowry acid-catalyzed COM reaction development.

Development of phosphoramide catalysts for carbonyl-olefin metathesis

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