Author Listing - Lead/ Submitting Author (we will be communicating with this individual): Name, Institution, City and State where the work was done. Co-authors will be added in a separate section.
GEORGINA DEL CISNE JADÁN LUZURIAGA
Instituto do Coração InCor, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo. São Paulo, Brazil
Main Body of the Abstract
Introduction. Deposition of transthyretin amyloid in cardiac tissue cause structural alterations and consequently ventricular arrhythmia. Purpose. To describe clinical and imaging characteristics between two groups, one with NSVT and other without this condition, evaluated on Holter monitoring. Methods. Retrospective analysis of patients with transthyretin amyloidosis, derived from the multicenter registry REACT-SP in Brazil. The data were collected from February 11, 2022, until February 5, 2024. Results: 180 patients analyzed (37 NSVT: 37 and 143 No-NSVT) (Table 1). The highest age was in the group with NSVT when compared with No-NSVT (73.0 vs 56.0 years, p=0.002). Male sex, ATTRv form. dyspnea and dizziness were associated with NSVT. BNP levels were most elevated when showed NSVT (p=0.002). Median LVEF was 53.0% and 62.0% in NSVT and No-NSVT, respectively (p=0.671) (Figure 1). Conclusion: We have discovered that NSVT was related to higher age, BNP levels, IVS and PWT diameters. Furthermore, the women and the preserved LVEF were most frequent when they didn’t have it.

**Author Listing - Lead/ Submitting Author (we will be communicating with this individual): Name, Institution, City and State where the work was done. Co-authors will be added in a separate section.**
GEORGINA DEL CISNE JADÁN LUZURIAGA
Instituto do Coração InCor, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo. São Paulo, Brazil
**Main Body of the Abstract**
**Introduction**. Deposition of transthyretin amyloid in cardiac tissue cause structural alterations and consequently ventricular arrhythmia. **Purpose**. To describe clinical and imaging characteristics between two groups, one with NSVT and other without this condition, evaluated on Holter monitoring. **Methods**. Retrospective analysis of patients with transthyretin amyloidosis, derived from the multicenter registry REACT-SP in Brazil. The data were collected from February 11, 2022, until February 5, 2024. **Results**: 180 patients analyzed (37 NSVT: 37 and 143 No-NSVT) (Table 1). The highest age was in the group with NSVT when compared with No-NSVT (73.0 vs 56.0 years, p=0.002). Male sex, ATTRv form. dyspnea and dizziness were associated with NSVT. BNP levels were most elevated when showed NSVT (p=0.002). Median LVEF was 53.0% and 62.0% in NSVT and No-NSVT, respectively (p=0.671) (Figure 1). **Conclusion**: We have discovered that NSVT was related to higher age, BNP levels, IVS and PWT diameters. Furthermore, the women and the preserved LVEF were most frequent when they didn’t have it.

Ventricular arrhythmia in transthyretin cardiac amyloidosis in a brazilian populations: outcomes of transthyretin cardiac amyloidosis registry in the state of São Paulo (REACT-SP)  PB19 (#563)

We invite you to attend the XIX International Symposium on Amyloidosis to be held in Rochester, MN.

This symposium is organized as a hybrid meeting (with the focus on in-person) held from Sunday, May 26 through Thursday, May 30, 2024.

Together with the ISA Board and members of Mayo Clinic, a very attractive scientific hybrid program is being planned. The program will cover a variety of types of systemic amyloidosis: ATTR (hereditary and wild-type), AL (light-chain), AA and less frequent forms. There will be key lectures, specific symposia including those company sponsored, oral presentations and poster sessions of accepted abstracts.

COURSE DESCRIPTION
This program will provide a comprehensive review of state-of-the-art education in systemic amyloidosis: basic science, pathophysiology, diagnosis, current and emerging treatments. Scientific presentations will include competitive oral and poster abstracts. The rapid evolution of scientific discovery and expanding treatment options has created tremendous interest in the field and this meeting will fill and important gap in educating scientists and clinicians.