Introduction/Hypothesis:
Pulmonary Angiosarcoma is a rare cancer found in blood/lymphatic vessels or on the skin surface. Most cases are cutaneous lesions which may be seen on physical exam, but visceral lesions may only reveal themselves when tumor mass effect causes local compression and correlating symptoms. The incidence is 1:1,000,000 and is most likely found in white men over 70, post-radiation treatment. Angiosarcomas contribute roughly 1% of all sarcomas, which in and of themselves make up 1% of cancers. This patient is a 38yo man who initially presented to the ED at an outside institution for dyspnea. The patient underwent a CT scan which showed soft tissue density in the pulmonary artery, diagnosed with PE and treated with anticoagulation. The patient returned to the ED with progression of symptoms and re-visualization of the soft tissue density. The patient was then referred to MCF for evaluation. The patient underwent surgical resection at MCF with pathology-proven sarcoma and + margins. The tumor had metastasized to numerous distant sites including the brain, adrenal, liver, and retroperitoneum.

Methods
This patient's history and imaging was obtained from the EMR. This patient has been followed exclusively by Mayo Clinic Florida since beginning cancer treatment.

Results
This patient attempted to treat his cancer aggressively with a combination of radiation and chemotherapy options post-surgical resection. A combination of Doxorubicin and daily fractionated therapy was unable to halt disease progression. Unfortunately, this patient eventually succumb to his illness. 

Conclusion
Angiosarcoma is a rare aggressive cancer that is notoriously resistant to treatment. This patient suffered unfortunate circumstances of diffuse metastasis throughout the chest, abdomen, and pelvis which caused significant pain, emotional stress, and ultimately led to his death. Imaging of this mass initially prompted a diagnosis of pulmonary embolism which led to a delay in treatment and potentially life saving surgery. Clinicians should be aware of unique malignant presentations and continue to keep a wide differential when interpreting routine studies.

**Introduction/Hypothesis:**
Pulmonary Angiosarcoma is a rare cancer found in blood/lymphatic vessels or on the skin surface. Most cases are cutaneous lesions which may be seen on physical exam, but visceral lesions may only reveal themselves when tumor mass effect causes local compression and correlating symptoms. The incidence is 1:1,000,000 and is most likely found in white men over 70, post-radiation treatment. Angiosarcomas contribute roughly 1% of all sarcomas, which in and of themselves make up 1% of cancers. This patient is a 38yo man who initially presented to the ED at an outside institution for dyspnea. The patient underwent a CT scan which showed soft tissue density in the pulmonary artery, diagnosed with PE and treated with anticoagulation. The patient returned to the ED with progression of symptoms and re-visualization of the soft tissue density. The patient was then referred to MCF for evaluation. The patient underwent surgical resection at MCF with pathology-proven sarcoma and + margins. The tumor had metastasized to numerous distant sites including the brain, adrenal, liver, and retroperitoneum.

**Methods**
This patient's history and imaging was obtained from the EMR. This patient has been followed exclusively by Mayo Clinic Florida since beginning cancer treatment.

**Results**
This patient attempted to treat his cancer aggressively with a combination of radiation and chemotherapy options post-surgical resection. A combination of Doxorubicin and daily fractionated therapy was unable to halt disease progression. Unfortunately, this patient eventually succumb to his illness. 

**Conclusion**
Angiosarcoma is a rare aggressive cancer that is notoriously resistant to treatment. This patient suffered unfortunate circumstances of diffuse metastasis throughout the chest, abdomen, and pelvis which caused significant pain, emotional stress, and ultimately led to his death. Imaging of this mass initially prompted a diagnosis of pulmonary embolism which led to a delay in treatment and potentially life saving surgery. Clinicians should be aware of unique malignant presentations and continue to keep a wide differential when interpreting routine studies.

Pulmonary Angiosarcoma - An Unfortunate Distribution Center for Diffuse Metastasis

This course will explore basic and cutting-edge imaging techniques to improve patient care and hone individual skills in performance and interpretation of echocardiography, nuclear cardiology, cardiac computed tomography, and cardiovascular magnetic resonance imaging. Days will reinforce how cardiovascular imaging may improve comprehension in ischemic heart disease, structural heart disease, cardiomyopathies, and heart failure. Experts will utilize novel techniques to reinforce key topics including taped interventional cases and a strong emphasis on case presentations.